FR 122047 hydrochloride

CAS No. 130717-51-0

FR 122047 hydrochloride( 1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride | 4,5-Bis(4-methoxyphenyl-2-[(1-methylpiperazin-4-yl)carbonyl]thiazole, Hydrochloride )

Catalog No. M27630 CAS No. 130717-51-0

FR 122047 hydrochloride is a potent and selective inhibitor of COX-1 with IC50 of 28 nM and 65 μM for human recombinant COX-1 and COX-2, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 95 Get Quote
10MG 158 Get Quote
25MG 323 Get Quote
50MG 520 Get Quote
100MG 745 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    FR 122047 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    FR 122047 hydrochloride is a potent and selective inhibitor of COX-1 with IC50 of 28 nM and 65 μM for human recombinant COX-1 and COX-2, respectively.
  • Description
    FR 122047 hydrochloride is a potent and selective inhibitor of COX-1 with IC50 of 28 nM and 65 μM for human recombinant COX-1 and COX-2, respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride | 4,5-Bis(4-methoxyphenyl-2-[(1-methylpiperazin-4-yl)carbonyl]thiazole, Hydrochloride
  • Pathway
    Chromatin/Epigenetic
  • Target
    COX
  • Recptor
    Antifection|HIV|Apoptosis|PI3K
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    130717-51-0
  • Formula Weight
    459.99
  • Molecular Formula
    C23H25N3O3S·HCl
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (217.40 mM)
  • SMILES
    O=C(C1=NC(C(C=C2)=CC=C2OC)=C(C(C=C3)=CC=C3OC)S1)N4CCN(C)CC4.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hu K, et al. Antifungal, antimitotic and anti-HIV-1 agents from the roots of Wikstroemia indica. Planta Med. 2000 Aug;66(6):564-7.
molnova catalog
related products
  • Continentalic acid

    Continentalic acid from Aralia continentalis has minimum inhibitory concentrations (MICs) of approximately 8-16 μg/mL against S. aureus.

  • Famprofazone

    Famprofazone (Gewodin, Gewolen) is a non-steroidal anti-inflammatory agent (NSAID) of the pyrazolone series .

  • 2-Amino-5-methyl-3-t...

    It is an organic compunds with molecular fomula C6H6N2S.