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FR 122047 hydrochloride
CAS No. 130717-51-0
FR 122047 hydrochloride( 1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride | 4,5-Bis(4-methoxyphenyl-2-[(1-methylpiperazin-4-yl)carbonyl]thiazole, Hydrochloride )
Catalog No. M27630 CAS No. 130717-51-0
FR 122047 hydrochloride is a potent and selective inhibitor of COX-1 with IC50 of 28 nM and 65 μM for human recombinant COX-1 and COX-2, respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 95 | Get Quote |
|
| 10MG | 158 | Get Quote |
|
| 25MG | 323 | Get Quote |
|
| 50MG | 520 | Get Quote |
|
| 100MG | 745 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameFR 122047 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionFR 122047 hydrochloride is a potent and selective inhibitor of COX-1 with IC50 of 28 nM and 65 μM for human recombinant COX-1 and COX-2, respectively.
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DescriptionFR 122047 hydrochloride is a potent and selective inhibitor of COX-1 with IC50 of 28 nM and 65 μM for human recombinant COX-1 and COX-2, respectively.
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In Vitro——
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In Vivo——
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Synonyms1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride | 4,5-Bis(4-methoxyphenyl-2-[(1-methylpiperazin-4-yl)carbonyl]thiazole, Hydrochloride
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PathwayChromatin/Epigenetic
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TargetCOX
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RecptorAntifection|HIV|Apoptosis|PI3K
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Research Area——
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Indication——
Chemical Information
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CAS Number130717-51-0
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Formula Weight459.99
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Molecular FormulaC23H25N3O3S·HCl
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (217.40 mM)
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SMILESO=C(C1=NC(C(C=C2)=CC=C2OC)=C(C(C=C3)=CC=C3OC)S1)N4CCN(C)CC4.Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Hu K, et al. Antifungal, antimitotic and anti-HIV-1 agents from the roots of Wikstroemia indica. Planta Med. 2000 Aug;66(6):564-7.
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