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FR 122047 hydrochloride

CAS No. 130717-51-0

FR 122047 hydrochloride( 1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride | 4,5-Bis(4-methoxyphenyl-2-[(1-methylpiperazin-4-yl)carbonyl]thiazole, Hydrochloride )

Catalog No. M27630 CAS No. 130717-51-0

FR 122047 hydrochloride is a potent and selective inhibitor of COX-1 with IC50 of 28 nM and 65 μM for human recombinant COX-1 and COX-2, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    FR 122047 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    FR 122047 hydrochloride is a potent and selective inhibitor of COX-1 with IC50 of 28 nM and 65 μM for human recombinant COX-1 and COX-2, respectively.
  • Description
    FR 122047 hydrochloride is a potent and selective inhibitor of COX-1 with IC50 of 28 nM and 65 μM for human recombinant COX-1 and COX-2, respectively.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    1-[(4,5-Bis(4-methoxyphenyl-2-thiazoyl)carbonyl]-4-methylpiperazine, Hydrochloride | 4,5-Bis(4-methoxyphenyl-2-[(1-methylpiperazin-4-yl)carbonyl]thiazole, Hydrochloride
  • Pathway
    Chromatin/Epigenetic
  • Target
    COX
  • Recptor
    Antifection|HIV|Apoptosis|PI3K
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    130717-51-0
  • Formula Weight
    459.99
  • Molecular Formula
    C23H25N3O3S·HCl
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (217.40 mM)
  • SMILES
    O=C(C1=NC(C(C=C2)=CC=C2OC)=C(C(C=C3)=CC=C3OC)S1)N4CCN(C)CC4.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hu K, et al. Antifungal, antimitotic and anti-HIV-1 agents from the roots of Wikstroemia indica. Planta Med. 2000 Aug;66(6):564-7.
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